Unlocking cell identity: RNA sequestration in P-bodies directs cell fate transitions

A new study published in Nature Biotechnology shows that stem cell differentiation is linked to cellular structures called ...
SciTech Daily

New Tool Reads DNA and RNA in a Single Cell, Unlocking Secrets of Disease

For centuries, scientists have recognized that certain illnesses can run in families, an idea that dates back to Hippocrates. Over time, researchers have become increasingly skilled at uncovering how ...
C&EN

Enhanced RNA Preservation in Mouse Brain Tissue: A Strategy Combining Cardiac Perfusion with Hypersaline Immersion

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. One of the key research methods for low-density spatial transcriptomics involves ...
FierceBiotech

Langer family RNA biotech Soufflé rises with $200M and Big Pharma partners

A new RNA biotech has risen with a $200 million series A in the tank and a team of seasoned biotech chefs ready to light the burners. Soufflé Therapeutics will cook up siRNA medicines that are ...
Medical Xpress

Drug discovery platform yields optimized compound against SARS-CoV-2 and shows promise against other RNA-based viruses

In a quest to develop new antiviral drugs for COVID-19 and other diseases, a collaboration led by scientists at The Wertheim UF Scripps Institute has identified a potential new drug against the virus ...
Phys.org

RAEFISH technique offers bigger and better window into RNA activity in complex tissue

For the first time, scientists can view RNA molecules directly inside cells and tissue in minute detail and across the entire human genome concurrently, thanks to new technology created by a Yale ...
eLife

Macroscopic Analyses of RNA-Seq Data to Reveal Chromatin Modifications in Aging and Disease

This valuable study analyzes aging-related chromatin changes through the lens of intra-chromosomal gene correlation length, which is a novel computational metric that captures spatial correlations in ...
Business Wire

Tempus Receives U.S. FDA 510(k) Clearance for Tempus xR IVD, its RNA NGS In Vitro Diagnostic Device

CHICAGO--(BUSINESS WIRE)--Tempus AI, Inc. (NASDAQ: TEM), a technology company leading the adoption of AI to advance precision medicine and patient care, today announced it has received 510(k) ...
C&EN

Biotech heavyweights band together for RNA start-up

Two biotech leaders, John Maraganore and Clive Meanwell, are embarking on what Maraganore is calling their third act together: a new start-up called Corsera Health. Their first act together, as ...
IEEE

kmmDE: a Non-parametric Method for Differential Expression Analysis of Time-course RNA-seq Data Using Maximum Mean Discrepancy

Abstract: Accurately identifying differentially expressed genes from time-course RNA-Seq data is essential for understanding the dynamics of transcriptome changes during biological processes. Although ...
WebMD

Dawnzera: First RNA-Targeted Therapy to Prevent Hereditary Angioedema Attacks

Dawnzera (donidalorsen) is a new medicine approved to help prevent attacks of a rare genetic swelling disorder known as hereditary angioedema (HAE) in people aged 12 or older. Affecting about 7,000 ...
Scientific American

How RNA Unseated DNA as the Most Important Molecule in Your Body

We’re celebrating 180 years of Scientific American. Explore our legacy of discovery and look ahead to the future. In 1957, just four years after Francis Crick and other scientists solved the riddle of ...