This important study examines the potential role of ARHGAP36 transcriptional regulation by FOXC1 in controlling sonic hedgehog signaling in human neuroblastoma. While there are many solid findings ...

Abstract: Recently, cross-domain few-shot facial expression recognition (CF-FER), which identifies novel compound expressions with a few images in the target domain by using the model trained only on ...

Primary open-angle glaucoma (POAG) is among the leading causes of irreversible blindness. Early detection and treatment are crucial for vision preservation, and research to identify genes associated ...

In our studies, we used a self-inactivating lentiviral vector containing a shortened elongation factor-α mammalian promoter driving ADA transgene expression. Our results from a large single cohort of ...

A Washington man appeared to be destined to develop Alzheimer’s disease — but against all genetic odds, he has eluded the common dementia for decades. Researchers at the Washington University School ...

With her husband, Dan, she ran four theaters in Manhattan and a company that distributed foreign and independent classics. By Sam Roberts Toby Talbot, who with her husband, Dan, cultivated an erudite ...

Regeneron is clearing a regulatory path for its investigational gene therapy DB-OTO after an early phase study demonstrated hearing improvements in children with a genetic form of deafness. The data, ...

Background: The associations between the rs7799039 variant in the promoter region of the leptin gene (LEP) and the rs1137100, rs1137101, and rs1805094 variants in the exons of the leptin receptor gene ...

Genetic deficiency of otoferlin, a protein critical to synaptic transmission by the sensory hair cells of the ear, causes congenital deafness. Medicines to treat the condition are lacking; children ...