pharmaphorum

Alnylam’s vutrisiran aces ATTR cardiomyopathy readout

Alnylam is riding high today after reporting its RNAi drug vutrisiran showed across-the-board efficacy in cardiomyopathy associated with transthyretin-mediated amyloidosis (ATTR), setting up ...
InfoWorld

Intro to Hotwire: HTML over the wire

This concept isn’t new—in fact, it is the essence of representational state transfer (REST). Instead of converting to a ...
pharmaphorum

Alnylam's ATTR cardiomyopathy drug backed for NHS use

Patients in England and Wales with cardiomyopathy caused by the disorder ATTR amyloidosis will soon be able to access treatment with Alnylam's gene-silencing drug Amvuttra. The ruling by reimbursement ...
findnerd.com

jQuery .prop() vs .attr()

Get the value of an attribute for the first element in the set of matched elements. An attribute value may only be a string. The attributes contains basic information ...
Health.com

4 Factors That Affect Your Transthyretin Amyloidosis (ATTR) Prognosis

Angela Ryan Lee, MD, FACC, is a board-certified cardiology and internal medicine physician. She also holds board certifications from the American Society of Nuclear Cardiology and the National Board ...
FiercePharma

Pfizer reported an ATTR sales decline in the US. Should newer market entrants Alnylam and BridgeBio worry?

The burgeoning field of transthyretin amyloid cardiomyopathy (ATTR-CM), which spurred excitement over a potential $20 billion market, may have just revealed the first indication of a slowdown. For the ...
Health.com

Signs and Symptoms of Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Transthyretin amyloid cardiomyopathy (ATTR-CM) is a condition that makes the heart stiff and less flexible, making it harder for the heart to pump. ATTR-CM doesn't always cause symptoms. When it does, ...
PharmaTimes

NICE recommends vutrisiran for adults with ATTR-CM in final draft guidance

First long-acting therapy with three-monthly dosing to target root cause of cardiac disease The National Institute for Health and Care Excellence (NICE) has issued final draft guidance recommending ...
Everyday Health

What You Need to Know About ATTR-CM When You’re an Older Adult

ATTR-CM can be a life-changing diagnosis, and if you’re an older adult, it can have an especially large impact on your quality of life. Transthyretin amyloidosis cardiomyopathy (ATTR-CM) is a rare but ...
Investing

Novo Nordisk begins Phase 3 trial for ATTR amyloidosis treatment

ATTR amyloidosis with cardiomyopathy is a condition where abnormal protein deposits build up in the heart, affecting its function. Current treatments for ATTR-CM focus on stabilizing or reducing ...
Seeking Alpha

Intellia: Moving To 'Hold' Rating In Light Of Nex-Z Uncertainty In ATTR Patients (Downgrade)

The last time I spoke about Intellia Therapeutics (NTLA), it was with a Seeking Alpha article entitled "Nex-Z Advancement Remains On Track With Expanded ATTRv-PN Indication" With respect to this ...
Healthline

7 Complications of Transthyretin Amyloidosis (ATTR)

Over time, transthyretin amyloidosis (ATTR) can damage the nerves, heart, and other organs. This may lead to complications like heart problems, nerve damage, and trouble with everyday bodily functions ...