The same cellular renewal that keeps our bodies healthy might also fuel the growth of cancer. A UC Merced biologist has found that the brain could hold the key to stopping it.

Tumors were eradicated in 30% of mice receiving cGAS LNPs injected into the tumor, in combination with immune checkpoint blockade.

"These RNAs seem to act like postal codes for gene repression," said Dr. Anuj K. Verma, lead author of the study. "They help direct the polycomb complex to precise chromatin neighborhoods where stress ...

Although heart cells and skin cells contain identical instructions for creating proteins encoded in their DNA, they're able ...

Michael Buck, PhD, professor of biochemistry in the Jacobs School, recently received NIH funding to explore how molecular readers of DNA access and activate seemingly hidden genes.

In a world first, a bespoke gene-editing therapy benefited one child. Now researchers plan to launch a clinical trial of the approach ...