If our genes are so similar, what really makes a eukaryote different from a prokaryote, or a human from E. coli? The answer lies in the difference in gene expression and regulation used. Regulation of ...

Genes encode proteins and proteins dictate cell function. Therefore, the thousands of genes expressed in a particular cell determine what that cell can do. Moreover, each step in the flow of ...

For decades, synthetic biologists have been developing gene circuits that can be transferred into cells for applications such as reprogramming a stem cell into a neuron or generating a protein that ...

Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...

A mission to search for the origin-of-life on Titan, Saturn's largest moon, will be aided by University of Otago – Ōtākou ...

Cyclone is a portable gene-switch system that uses acyclovir to reversibly control gene expression with minimal toxicity.

Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of ...

Early-stage lung adenocarcinoma alters DNA methylation, mRNA transcription, and protein expression in adjacent tissues, exhibiting either steep changes at the tumor boundaries or shallow changes ...

A research team at the Max Planck Institute for Chemical Ecology has successfully combined single-cell RNA sequencing (scRNA-seq) and single-cell mass spectrometry (scMS) analysis on the same plant ...

Our experiences leave traces in the brain, stored in small groups of cells called "engrams". Engrams are thought to hold the ...

Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of ...