KATMAP: A new way to understand and predict gene splicing

Although heart cells and skin cells contain identical instructions for creating proteins encoded in their DNA, they're able ...
Johns Hopkins Medicine

Nobel Laureate Hamilton Smith, Who Discovered Molecular ‘Scissors’ to Cut DNA, Dies at 94

Johns Hopkins University School of Medicine alumnus and former faculty member Hamilton O. Smith, M.D., whose 1978 Nobel Prize-winning discovery of restriction enzymes revolutionized genetic ...

Molecular dynamics simulations use atomistic force field to capture RNA folding with high accuracy

Ribonucleic acid (RNA) is one of life's most versatile molecules, with roles going far beyond being a messenger of genetic ...

Decoding how cells choose to become muscles or neurons

Every cell in the body has the same DNA, but different cell types—such as muscle or brain cells—use different parts of it.
Jacobs School of Medicine and Biomedical Sciences - University at Buffalo

Uncovering the Rules of DNA’s Hidden Language

Michael Buck, PhD, professor of biochemistry in the Jacobs School, recently received NIH funding to explore how molecular readers of DNA access and activate seemingly hidden genes.
IEEE Spectrum on MSN

Inside the Massive Effort to Sequence All of Europe’s Lepidoptera

It’s a little after 6:30 on a brisk July morning in a stone hut high in the Italian Alps. A gently hissing wood fire is ...
Scientific American

Gene Editing Helped One Baby—Could It Help Thousands?

In a world first, a bespoke gene-editing therapy benefited one child. Now researchers plan to launch a clinical trial of the approach ...