With a newly developed method that compares AI-generated protein sequences with naturally occurring ones, function- and ...

This fully updated volume explores a wide array of new and state-of-the-art tools and resources for protein function prediction. Beginning with in-depth overviews of essential underlying computational ...

The complexity and heterogeneity of protein therapeutics present significant challenges in biologics discovery, as ...

Ion channels generate electrical impulses produced by living cells. Synthetic ion channels could serve as tools for ...

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, intriguingly, many of the most important proteins involved in gene ...

Researchers used cryo-EM to study how the HIV enzyme integrase arranges in 3D to slip its DNA into the host genome and pack ...

ESMs, a proteome-scale framework to classify loss-of-function missense variants into distinct mechanistic groups by combining two complementary state-of-the-art machine learning models. The strength ...

Breakthrough cryo-EM structures expose multiple drug targets in an essential HSV-1 replication protein.An international ...

Scientists from the University of Nottingham's School of Pharmacy and Department of Chemical and Environmental Engineering, ...