Sir2, an enzyme belonging to sirtuins, has been shown to be involved in the deacetylation of proteins. Researchers from the ...

ESMs, a proteome-scale framework to classify loss-of-function missense variants into distinct mechanistic groups by combining two complementary state-of-the-art machine learning models. The strength ...

The enzyme PI3K plays a critical role in cell migration. Scientists have long understood this function. But researchers have recently unveiled that a subunit of this enzyme also has the ability to ...

Peroxisomes are essential cell organelles that play a vital role in lipid metabolism and cellular detoxification. To perform ...

An international research team has published a study in the journal The FEBS Journal that significantly advances the knowledge of a rare hereditary metabolic disease: classical homocystinuria. The ...

Scientists discovered a key molecular switch to keep neurons healthy by controlling the disassembly and assembly of their energy-generating powerhouses, the mitochondria. The study illustrates how a ...

Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes. An organelle is a small structure in a cell that is ...

This story is one in a series marking International Women and Girls in Science Day. Join us as we celebrate some laboratory leaders taking research to new heights. Enzymes are the fundamental stuff of ...