Peroxisomes are essential cell organelles that play a vital role in lipid metabolism and cellular detoxification. To perform ...

ESMs, a proteome-scale framework to classify loss-of-function missense variants into distinct mechanistic groups by combining two complementary state-of-the-art machine learning models. The strength ...

Long Interspersed Nuclear Element-1 (LINE-1 or L1) is the only active, self-copying genetic element in the human ...

Long interspersed nuclear element-1 (LINE-1 or L1) is the only active, self-copying genetic element in the human ...

Activation of the complement cascade of proteases has been linked to autoimmune and kidney diseases, including systemic lupus ...

The immune system has a tough job: When a tiny virus invades one of our cells, that cell must detect it and, within minutes, ...

A cell’s “death fold domain” protects our bodies from infection at the risk of chronic inflammation, essentially “trading ...

Japanese researchers have uncovered how the astringent “bite” of cocoa flavanols can activate the brain—even though little of the compound enters the bloodstream.

This study presents valuable findings on the role of KLF6 in in vitro endothelial cells exposed to altered (high or low) shear stress with a customized microfluidic device to investigate mechanisms of ...

The world’s deadliest infectious disease urgently requires new and effective antibiotics. Researchers have created a promising new compound that may mark a major step forward in the global effort to ...