BMJ

Widening access to isotretinoin in primary care: an evaluation of New Zealand national dispensing data for isotretinoin for acne, 2008–2023

Objectives To identify what changes in the prescribing of isotretinoin have occurred since funded prescriber access was widened in 2009 from ‘dermatologist only’ prescribing to include ‘general ...
IEEE

Integrating Deep Learning and SHAP for Breast Cancer Classification and Biomarker Discovery Using Gene Expression Data

Abstract: This study explores the application of deep learning models combined with SHAP (SHapley Additive exPlanations) for breast cancer classification using gene expression data. Our model ...
BioSpace

Antengene Presents Latest ATG-022 Clinical Data at ESMO 2025 Demonstrating Efficacy Across All CLDN18.2 Expression Levels and Exceptional Tolerability

ATG-022 is a CLDN18.2-targeted ADC with sub-nM affinity and fast internalization. Using a VC-MMAE linker-payload (DAR 4), ATG-022 has demonstrated potent activity across tumors with high, low, and ...
The News Minute

Police and lower courts are failing SCs and Muslims in TN, prison data shows

Would you believe it if I told you that Tamil Nadu has the highest number of Scheduled Caste (SC) undertrials in the country? Or if I told you that in Tamil Nadu, the proportion of Muslims in jails is ...
IEEE

Large-Scale Data Quality Challenges, Framework and Evaluation in Metro Systems

Abstract: Data quality is a fundamental challenge for downstream data mining tasks. While numerous studies have addressed data quality issues in various contexts, there is a notable lack of systematic ...
C&EN

Cryo-EM Structure of the Cyclase Domain and Evaluation of Substrate Channeling in a Bifunctional Class II Terpene Synthase

Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States Graduate Group in Biochemistry, Biophysics, and ...