Novel molecular mechanisms shape neuron identity in retinal cells

A recent study led by Tiffany Schmidt, Ph.D., associate professor of Ophthalmology and of Neurobiology in the Weinberg ...

Pathway provides new insight into how cilia on cell surfaces break down before division

In many cells of the human body, hair-like protrusions known as cilia act as antennae, allowing cells to receive signals from ...
EMBO Press

From denaturant to ribosome: rethinking chaperone requirements in cells

DnaK/DnaJ or Trigger factor and find that chaperone dependence during primary biogenesis in vivo does not track with ...
Nature

Crystal structure of the class D β-lactamase OXA-10

We report the crystal structure of a class D β-lactamase, the broad spectrum enzyme OXA-10 from Pseudomonas aeruginosa at 2.0 Å resolution. There are significant differences between the overall fold ...
EMBO Press

Mechanism of autophagy initiation by transmembrane selective autophagy receptors

Selective autophagy ensures the targeted degradation of damaged or surplus cellular components, including organelles, thereby ...