Advances in cancer immunotherapy from immune checkpoint modulation to adoptive cell transfer of tumour-infiltrating ...

Lehigh University bioengineering researcher Tomas Gonzalez-Fernandez, an assistant professor in the P.C. Rossin College of Engineering and Applied Science leads an interdisciplinary team applying ...

Traditional breeding and genetic modification methods have struggled to keep pace with the rapid evolution of plant viruses. CRISPR/Cas systems, originally derived from bacterial immune responses, ...

Scribe’s CRISPR epigenetic silencing technology, ELXR, demonstrated dramatic and sustained lowering of LDL-C by up to 67% for nearly 6 months in non-human primates – without altering DNA sequence. In ...

Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...

Nkarta, Inc. (Nasdaq: NKTX), a clinical-stage biopharmaceutical company developing engineered natural killer (NK) cell therapies, today announced its participation in the following investor ...

New Rochelle, NY, October 22, 2024—An invited Guest Editorial entitled “Give Cas a Chance,” by Fyodor Urnov, PhD, Director of Technology & Translation at the Innovative Genomics Institute (IGI), ...

For many people interested in genome engineering, the era “before CRISPR” has faded into the deepest recesses of the mind, like a lost period of antiquity, even though it only entered the biotech ...

When Integrated DNA Technologies (IDT) was founded in 1987 by Dr. Joseph Walder, he set his sights on a bold company vision. He believed that synthetic nucleic acids—known as oligonucleotides (oligos) ...

The mice model technologies market offers significant opportunities driven by advancements in genetic engineering, particularly CRISPR/Cas9, fueling drug discovery in oncology, neurobiology, and ...