A new reverse genetics system for norovirus could aid in the development of novel antiviral therapies and vaccines.

Recent advances in cell culture technology have transformed the landscape of viral vaccine production, offering enhanced scalability, efficiency and adaptability compared to traditional egg‐based or ...

Researchers from The University of Osaka have developed a novel reverse genetics system to study norovirus, the leading cause of gastroenteritis. This efficient system can generate infectious viral ...

Recently, Prof. Si Longlong's team from the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences constructed a library of live-attenuated influenza A vaccines that utilize ...

COVID-19 vaccines lower the risk of getting sick, seriously ill or dying from the disease. But how do the different types of COVID-19 vaccines work? Each COVID-19 vaccine causes the immune system to ...

Live attenuated vaccines mimic natural infections, providing strong immunity but require refrigeration and caution for immunocompromised individuals. Subunit vaccines offer targeted immunity without ...

Viral membrane proteins are the proteins of choice in vaccines but are difficult to produce quickly and reliably for use in vaccines, limiting rapid response during emerging outbreaks. Researchers ...

Vaccines that resemble viruses generally produce a stronger immune response, while mRNA versions are much quicker and cheaper to make. Now we are getting the best of both worlds, in the form of mRNA ...

Researchers have developed EVE-Vax, a computational design tool that creates synthetic SARS-CoV-2 spike proteins mimicking future immune-evading variants. These designed proteins enable early ...