A robust primary immune response has been correlated with the precursor number of antigen-specific T cells, as identified using peptide MHCII tetramers. However, these tetramers identify only the ...
Elevated PD-1+CD4+ T cells represent an independent risk factor for lupus nephritis (LN) and may serve as a biologically meaningful diagnostic and therapeutic target.
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Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus
Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by ...
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