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Dietary restriction boosts antitumour immunity by rewiring T cell metabolism
Dietary restriction reshapes CD8+ T cell metabolism by increasing ketone body–driven acetyl-CoA production, preventing ...
News-Medical.Net on MSN
Poor dietary iron weakens lung memory T cells after flu infection
Dietary iron deficiency in mice alters lung T cell activation during influenza infection and leads to memory T cells that are ...
News Medical on MSN
JMC Publication: Insilico’s AI platforms enable discovery of potent, selective, oral DGKα inhibitor to overcome checkpoint resistance
Novel, Potent, Selective and Orally Available DGKα Inhibitors for the Treatment of Tumors view more . Credit: Insilico ...
The field of immunology of ageing is rapidly evolving, with T cells playing a pivotal role in maintaining immune competence and overall organismal ...
News Medical on MSN
Scientists reveal how tumor-cell MHC-II drives immunotherapy success
Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor ...
Murine data suggest dietary iron deficiency preserves influenza specific memory T cell numbers yet impairs cytokine effector ...
Hepatocellular carcinoma (HCC) is the sixth leading cause of cancer-related mortality worldwide.1 Despite therapeutic ...
BioInvent International (STO:BINV) 46% objective response rate (6 of 13 evaluable patients) and a 92% disease control rate ...
New research published in The Journal of Immunology suggests that a lack of dietary iron can negatively affect the ability of ...
Serious side effects, including neurotoxicity and intestinal inflammation, that appear weeks or months after patients receive ...
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