The interleukin-6 receptor (IL-6R) is the receptor that IL-6 binds to in order to initiate the body’s responses to inflammation and infection. Interleukin 6. Image ...

A Mayo Clinic investigation of Interleukin-6, a hormone inside cells often considered a "bad actor" of the immune system because of its association with inflammation injuries and malignant ...

Researchers have identified a novel strategy to reduce immune-related adverse events from immunotherapy treatment by targeting the cytokine interleukin-6 (IL-6). Researchers at The University of Texas ...

CI denotes confidence interval, and SNP single-nucleotide polymorphism. Sequencing reads were aligned to the hg19 reference genome. A SIFT (sorting intolerant from tolerant) score of less than 0.05 ...

The Janus kinase/signal transducer and activator of transcription (Jak/Stat) pathway was discovered 20 years ago as a mediator of cytokine signaling. Since this time, more than 2,500 articles have ...

In 1973, interleukin 6 (IL-6) was detected as a soluble factor that is secreted by T cells. It is crucial for the generation of antibodies through B cells. The IL-6 signaling pathway has become a ...

Interleukin-6 (IL-6) is a pleiotropic cytokine that may play a role in the regulation of various aspects of the immune response, inflammation, hematopoiesis, and bone metabolism. IL-6 acts by binding ...

Data are presented as median (min–max). a P 0.05 vs controls; b P 0.01 vs controls; c P 0.001 vs controls; d P 0.05 vs IIA+IIB group Abbreviations: ApoA-I, apolipoprotein A-I; ApoB, apolipoprotein B; ...