Increased uric acid excretion could explain, at least in part, the renoprotective effects of SGLT2 inhibitors. The kidney-protective effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors in ...

HYDROCHLOROTHIAZIDE (6-chloro-7-sulfamyl-3,4,dihydro-l,2,4, benzothiadiazine-1,1,-dioxide) is the 3,4,dihydro derivative of chlorothiazide wherein the 3,4 double bond is saturated by two hydrogen ...

Renal drug excretion involves filtration, reabsorption, and secretion, crucial for drug clearance and minimizing toxicity. The study models renal clearance using pharmacokinetic parameters, validated ...

Excretion is the process of removal of toxic wastes from the body of an organism. The major wastes produced by us are: Carbon dioxide and Urea. Carbon dioxide is produced by the process of respiration ...

Chronic kidney disease (CKD) is a syndrome defined as persistent alterations in kidney structure, function or both with implications for the health of the individual 1,2. Examples of structural ...

“You’re on a chemotherapeutic and your oncologist may say that your dosage is X, while a nephrologist is telling you that the proximal tubules in your kidneys can’t handle it. You’re harming them.” ...