A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall ...

Nerandomilast's tolerability and dual antifibrotic/immunomodulatory mechanism directly address the critical non-adherence ...

The GNPS Drug Library may be more broadly applicable for drug screening across diverse research disciplines, such as food and environmental monitoring.

But the mechanism of action of a major monoclonal antibody developed for ulcerative colitis has remained elusive—until now. The antibody is known as vedolizumab (VDZ) and it is prescribed under the ...

HONOLULU — Glovadalen (UCB), an investigational brain-penetrant D1 receptor positive allosteric modulator (D1 PAM), is both safe and effective for patients with advanced Parkinson’s disease (PD), new ...

The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the neurochemical ...

Cedars-Sinai scientists have developed an experimental drug that lab studies show can repair tissues damaged by common diseases.