Changing levels of the brain protein KCC2 can alter how reward associations form, reshaping the learning process that links ...

Researchers report October 25 in the journal Neuron that cocaine addiction disrupts the dopamine neurons that govern how we perceive and learn from rewards. Though people with cocaine addiction have ...

Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that ...

New research shows that astrocytes play an active role in nicotine-induced brain changes, challenging the long-held ...

(SALT LAKE CITY)—As the new University of Utah School of Dentistry readies to open the doors to its first four-year class in the fall of 2013, the program has landed more than $5 million in two grants ...

Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific "anti-reward" brain circuit becomes hyperactive during withdrawal-driving ...

Israel-based psychedelics biotech Clearmind Medicine Inc. CMND shared additional positive results on the impact of the MEAI molecule in the natural reward process in an in-vivo preclinical study of ...

Scientists are testing whether GLP-1 drugs can help to cut cravings for cigarettes, alcohol and opioids — as well as food.

Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the drugs' ...

The medications have grown popular for weight loss, but one doctor has found another use: combating alcohol and drug addiction.

More than 48 million Americans have struggled with a substance use disorder (SUD) over the last 12 months. Despite decades of research and treatment interventions, relapse rates remain stubbornly high ...

A breakup or the loss of a loved one can feel like you're in withdrawal. Their absence can feel like yearning, physical pain — like an addiction no longer fed. And it's that feeling of addiction that ...