The AHA recommended whole exome or whole genome sequencing as first-line diagnostic tools for mitochondrial diseases.

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...

A new study from deCODE genetics uses pedigrees and sequence data from 64,806 Icelanders to shed light on the rate and nature of mutations in mitochondrial DNA (mtDNA) and the peculiar dynamics of its ...

Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have been observed in cancer, but it has been unclear how these changes might ...

A research team has identified a molecular target that could open up new therapeutic options to treat aging-associated diseases like Parkinson's. Scientists at the University of Cologne have ...

You are a forensic scientist recruited to help solve a long-standing "missing persons" case. Mitochondrial DNA, or mtDNA for short, is the key to your success. Take careful notes as your teacher ...

There are a total of 5 multi-subunit complexes in the inner membrane of the mitochondria, all of which are involved in the process of oxidative phosphorylation that precedes ATP production. Of these, ...

Understanding the relationship between mtDNA and animal growth could provide valuable information for selective breeding in aquaculture. However, the complex interactions between genetics and ...

When a four-year-old boy was brought to the Cincinnati Children’s Hospital Medical Center with fatigue, muscle pain and muscle weakness, doctors suspected there might be something wrong with his ...