Bacteria-attacking viruses, known as bacteriophages, use small RNAs to disarm the CRISPR-Cas immune systems of bacteria. This discovery has now been documented by researchers at the University of ...

Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...

Genetic modifications in reproductive cells, such as eggs, sperm, or embryos, are commonly referred to as germline editing and are heritable. 1 CRISPR-Cas 9, which stands for clustered regularly ...

Genetic mutations can alter how the proteins produced by our genes function and can lead to diseases like cancer. Now researchers have used the gene-editing technology CRISPR/Cas 9 in a less commonly ...

Scientists have revealed how Fanzor2's divergence from bacterial ancestors may make it a useful tool for future genomic engineering endeavors. A revolution in biomedicine is currently underway, driven ...

A microscopic discovery will not only enable scientists to understand the microbial world around us but could also provide a new way to control CRISPR-Cas biotechnologies. An international team of ...

Scientists at Leipzig University, in collaboration with colleagues at Vilnius University in Lithuania, have developed a new method to measure the smallest twists and torques of molecules within ...

Scientists introduced CRISPR to the world as a gene-editing tool in summer 2012, when landmark papers from two independent groups demonstrated how the system could be wielded to make cuts in DNA. Now, ...