Transmembrane proteins are essential for the survival and function of all living cells. They are involved in virtually every biological process, making them a vital target for drug development.

To stay healthy, our cells rely on a self-cleaning mechanism that removes defective or unnecessary components. This process, ...

STEAP1 (Six-transmembrane epithelial antigen of the prostate 1), which was first found in prostate cancer, is a member of the STEAP protein family that is largely expressed in prostate epithelial ...

Researchers decipher the function of an ion channel involved in cellular degradation processes and create new possibilities for Parkinson’s therapies.

A selective protein degradation system known as Golgi membrane-associated degradation (GOMED), which identifies and removes ...