Multiple sequence alignment (MSA) is a cornerstone of computational biology, facilitating the exploration of functional, structural and evolutionary relationships among biological sequences.
Subscribe to our newsletter for the latest sci-tech news updates. Open-access databases such as the European Nucleotide Archive (ENA) contain more than 2.4 million bacterial genomes, and this number ...
The gapped local alignment score of two random sequences follows a Gumbel distribution. If computers could estimate the parameters of the Gumbel distribution within one second, the use of arbitrary ...
Roestel, Jessica A., Wiersema, John H., Jansen, Robert K., Borsch, Thomas, and Gruenstaeudl, Michael. 2023. [Dataset] On the importance of correct DNA sequence alignment in plastid phylogenomics – an ...
In bioinformatics, the notion of an 'island' enhances the efficient simulation of gapped local alignment statistics. This paper generalizes several results relevant to gapless local alignment ...
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