A new paper published in Nature Biotechnology this week titled, “Template-independent enzymatic synthesis of RNA oligonucleotides,” provides details of a method for synthesizing single-stranded RNA ...
While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and ...
RNA-based medicines are transforming the way we treat disease—offering targeted, precision therapies for conditions ranging from rare genetic disorders to widespread chronic illnesses like diabetes, ...
A single enzyme that can generate all four nucleoside triphosphates, the building blocks of ribonucleic acid (RNA), has been identified by researchers at the Institute of Science Tokyo. The study was ...
As RNA therapeutics evolve far beyond their vaccine origins, a new generation of scientists and manufacturers is rethinking how to produce these complex medicines safely, efficiently, and at scale.
In all organisms, RNA synthesis is carried out by proteins - known as RNA polymerases (RNAPs) - that transcribe the genetic information from DNA in a highly-regulated, multi-stage process. RNAP is the ...
A single enzyme that can generate all four nucleotide triphosphates, the building blocks of ribonucleic acid (RNA), was ...
The discovery of catalytic RNA transformed our understanding of life's beginnings. Clare Sansom explores how the RNA world ...