Proteins are the end products of the decoding process that starts with the information in cellular DNA. As workhorses of the cell, proteins compose structural and motor elements in the cell, and they ...

In his lecture after winning a share of the 2002 Nobel Prize in Chemistry, John Fenn described his work as creating “wings for molecular elephants”. Fenn pioneered the use of a method called ...

This review provides an overview of traditional and modern methods for protein structure prediction and their characteristics and introduces the groundbreaking network features of the AlphaFold family ...

This year’s Lasker Basic Medical Research Award recognizes the contributions of Demis Hassabis and John Jumper for their invention of the AlphaFold artificial intelligence (AI) system, which predicts ...

As artificial intelligence (AI) predictions produce an explosion of three-dimensional protein structure data, a bottleneck is growing as interpretation fails to keep up with the deluge. In this ...