Escherichia coli remains at the forefront of recombinant protein production, owing to its rapid growth, well-characterised genetics and the ease with which it can be genetically manipulated. The ...

By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes long-standing trade-offs between maximizing expression metrics and maintaining ...

Small proteins, Vellappan emphasized, are emerging as key subjects of research. Scientists worldwide are seeking a deeper level of understanding about the myriad mechanisms underlying the function of ...

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The cost-effective, easy-to-use T7 expression system has been integral to Escherichia coli protein production since its introduction in 1986. Now, a just-developed enhancement is making it even better ...

Proteins are synthesized through two processes involving DNA: transcription, which converts DNA into mRNA; and translation, where ribosomes read the mRNA and sequentially link amino acids to form ...

This article is based on a poster originally authored by Sunidhi Shetty, Narasimha Murthy Bandaru, Anna Moberg and Marco Manni, which was presented at ELRIG Drug Discovery 2024 in affiliation with ...