The replication control system of plasmid R6-5 has been investigated by characterization of high-copy-number mutant miniplasmids, development of an in vivo assay for the site of action or ``target'' ...
HUH endonucleases contain the characteristic HUH motif (in which U represents a hydrophobic residue) and a Y motif, containing either one or two Tyr residues. HUH ...
Plasmid DNA (pDNA) is a fundamental starting material for therapeutic development, including for viral vectors, mRNA therapies, and DNA vaccines. Researchers use capture methods such as anion exchange ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, No. 13 (Jun. 21, 1994), pp. 5962-5966 (5 pages) In a search for trypanosome DNA sequences that permit ...
Adeno-associated virus (AAV) vectors play a pivotal role in gene therapy, delivering therapeutic genes with high precision and safety. However, a significant challenge in the biomanufacturing of these ...
Microbial systems offer distinct advantages in protein expression, saving costs and time, and offering well-characterized host genetics and ease of scale-up. 2 However, challenges remain in process ...
DNA-based information is a new interdisciplinary field linking information technology and biotechnology. The field hopes to meet the enormous need for long-term data storage by using DNA as an ...
Biology is no longer being hampered by the cell environment thanks to cell-free technology that makes it easier to clone DNA. Located in Tokyo, Japan, OriCiro Genomics is a pioneer in cell-free ...
DNA and RNA vaccines use genetic material to deliver information to human cells and elicit an immune response. DNA vaccines are safe, easy, affordable to produce, and, unlike RNA vaccines, are stable ...
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