Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth.

Study results indicate that mutation strength may shape both tumor–immune system interactions and immunotherapy response.

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth ...

A study led by Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., at MUSC Hollings Cancer Center, reveals why a specific gene mutation behaves differently from other variants.

When the TREX1 gene is functioning normally, it produces a protein that helps maintain DNA in cells throughout the body. Mutations in the TREX1 gene are known to cause a rare and serious disease ...

A newly discovered genetic mutation unique to humans may help explain why we are significantly more vulnerable to cancer than our closest evolutionary relatives. Researchers at the University of ...

Flinders University researchers have discovered a rare genetic mutation that could explain why some people do not respond to ...