Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...

Researchers at Duke University and North Carolina State University have discovered a handful of new CRISPR-Cas systems that could add to the capabilities of the already transformational gene editing ...

CRISPR/Cas9 works by having CRISPR (pieces of DNA sequences) guide Cas9 (an enzyme that can cut and edit DNA) to edit, alter, or repair genes. Intellia has leveraged its expertise in CRISPR/Cas9 gene ...

For some diseases, gene therapies offer the potential for lifelong disease amelioration and even cure. And these immensely important novel biotechnologies may be on the cusp of a boom. That is in part ...

A research team has successfully engineered a japonica rice variety using CRISPR/Cas9 to simultaneously optimize plant ...

Intellia Therapeutics has paused dosing in its Phase 3 MAGNITUDE trials after a patient experienced severe liver toxicity, as ...

Scientists study a molecular machine that moves jumping genes in DNA, paving the way for a new gene editing tool beyond CRISPR-Cas9. (Nanowerk News) More than a decade ago, scientists harnessed a ...

Researchers have discovered a handful of new CRISPR-Cas systems that could add to the capabilities of the already transformational gene editing and DNA manipulation toolbox. Of the new recruits, one ...

A detailed look at the predicted structure of a new CRISPR-Cas tool that promises to expand the genomic editing and manipulating abilities of the original. Researchers at Duke University and North ...