A new study finds that proteins known as linker histones control the complex coiling process that determines whether DNA will wind into long and thin chromosomes, made up of many small loops, or short ...

UCLA scientists have identified a new function for histones, the spool-shaped proteins that regulate gene expression and serve as anchors for strands of DNA to wrap around. The researchers discovered ...

UNFRACTIONATED preparations of histones from normal mammalian tissues have been reported to inhibit the growth of transplantable tumours in rats 1. Incubation of mucous cancer cells of liver with rat ...

The genetic material--DNA-- of plants and animals (within the latter humans) is stored inside the cell, and DNA packing is guaranteed by proteins called histones. Furthermore, histones play a key role ...

Nucleosomes are loaded onto pre-existing eukaryotic chromatin to maintain the structure of nuclear DNA. However, how retroviral DNA that enters cells during infection acquires nucleosomes de novo is ...

In our cells, 6 feet (1.8 m) of DNA gets crammed into chromosomes that fit inside a 6-µm-wide nucleus. The proteins that help pack up that genetic material are histones, which act as spools around ...

Scientists headed by Ferran Azorín at the Institute for Research in Biomedicine (IRB Barcelona) have discovered why histone 1 is a major protection factor against genomic instability and a vital ...

This article was originally featured on Knowable Magazine. Every second, as we breathe, sleep, eat and go about our lives, millions of biochemical reactions are happening in our cells. Among the hurly ...

Nearly two years into the pandemic, we find ourselves thinking about viruses daily. Amid the dread of hearing about yet another new SARS-CoV-2 variant and longing for normalcy, perhaps you’ve ...

The coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is a highly virulent virus. Evidence suggests that disruption of host ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation. Now, researchers from Kyushu University have demonstrated ...