Collaborating researchers have made a breakthrough discovery regarding the intricate defense systems of bacteriophages (phages)—viruses that can specifically target harmful bacteria without harming ...

Your DNA holds the blueprint to build your body, but it’s a living document: Adjustments to the design can be made by epigenetic marks. Cataloguing these marks and how they work is important for ...

DNA phosphorothioate modification is a distinctive epigenetic alteration in which a non‐bridging oxygen atom within the DNA sugar-phosphate backbone is replaced by ...

An important DNA modification is methylation, or the addition of a methyl group to the 5th carbon of cytosine. This forms 5-methylcytosine (5mC), typically associated with repression of gene ...

Scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) and collaborating institutions have developed a DNA-editing method that introduces small chemical modifications at ...

LMU molecular biologist Gunnar Schotta has investigated which mechanisms prevent endogenous retroviruses from becoming overly active. Endogenous retroviruses (ERVs) have established themselves in the ...

A UCLA-led study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin — DNA and proteins — plays a critical role.

Modifi Biosciences announced today that the journal Science has published a critical study validating the company's novel oncology platform based on new classes of molecules that exploit ...

Neuroscientists have uncovered a new mechanism for memory formation, and it involves changes in the structure of your DNA. If you were asked to picture a molecule of DNA, chances are you would ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...