The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.
MSP: Methylation-specific PCR; MSRE: Methylation-sensitive restriction endonucleases; QMSP: Quantitative, methylation-specific PCR; X: Methylation associated with prognosis. Mohammad Obaidul Hoque, ...