Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

Scientists at The Hospital for Sick Children (SickKids) are delving deep into the non-coding genome to unravel the complex genetics that underlie blood pressure regulation and hypertension (high blood ...

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

The DNA damage from ionizing radiation (IR) erupting from the Chernobyl nuclear disaster of 1986 is showing up in the ...

Sections of DNA once dismissed as dormant and useless could in fact be recruited to fight certain types of drug-resistant blood cancers, new research has revealed. One category of non-coding DNA is ...

Scientists studying Alzheimer's disease (AD) have identified thousands of genetic variants in the genome in the development of this progressive neurodegenerative disease. These variants are ...

Deep-learning model decodes the regulatory effects of DNA changes ...

For many years, scientists have known that genetic variants, or differences in DNA code across people, play some role in neurological and psychiatric disorders. But the details were murky. Now, ...

In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals.

MIT researchers have built an AI language model that learns the internal coding patterns of a yeast species widely used to ...