This new patented toolbox, complementing - and for certain applications surpassing - CRISPR, is now available for researchers and industry in the field of genome engineering. The results are reported ...

Traditional breeding and genetic modification methods have struggled to keep pace with the rapid evolution of plant viruses. CRISPR/Cas systems, originally derived from bacterial immune responses, ...

Lehigh University bioengineering researcher Tomas Gonzalez-Fernandez, an assistant professor in the P.C. Rossin College of Engineering and Applied Science leads an interdisciplinary team applying ...

Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...

Scribe’s CRISPR epigenetic silencing technology, ELXR, demonstrated dramatic and sustained lowering of LDL-C by up to 67% for nearly 6 months in non-human primates – without altering DNA sequence. In ...

CREATE Medicines, Inc. (formerly Myeloid Therapeutics) today announced new preclinical data for RetroT, the company's fully RNA-encoded, site-specific gene-integration system, presented at the Cold ...

(Nasdaq: NKTX), a clinical-stage biopharmaceutical company developing engineered natural killer (NK) cell therapies, today announced its participation in the following investor conferences next month: ...

For many people interested in genome engineering, the era “before CRISPR” has faded into the deepest recesses of the mind, like a lost period of antiquity, even though it only entered the biotech ...

The 2020 Nobel Prize in Chemistry was awarded for the development of CRISPR/Cas9, a method also known as "gene scissors," which enables researchers to better understand how human cells function and ...

When Integrated DNA Technologies (IDT) was founded in 1987 by Dr. Joseph Walder, he set his sights on a bold company vision. He believed that synthetic nucleic acids—known as oligonucleotides (oligos) ...