Cancer immunotherapies often rely on activating immune responses, yet many tumors remain resistant because their internal survival mechanisms are poorly understood.

Enrollment spans Europe, the US, and Canada, targeting ~324 GA patients in a randomized, double-masked, sham-controlled phase 2 program. Dosing compares two intravitreal dose levels given every 12 or ...

In a new study published in Cell Death & Disease, a team of researchers from the University of Michigan found functional ...

The cGAS-STING signaling pathway has emerged as a major focus in cancer immunotherapy because it stimulates interferon production and enhances antitumor immune responses. However, despite strong ...

Here’s what you’ll learn when you read this story: When cells are about to die, they send signals that trigger proteins which are supposed to destroy them, but it doesn’t always happen that way. Some ...